I have my monitor profiled at sRGB and PS, and my camera is set on sRGB.
There is a lot of conflicting data on this - I've read numerous books and talked to a lot of printers - none of them seem to be able to agree.
Totally photos upload function displays the image in sRGB but it's converted to RGB for display. I found out at TP because I uploaded a photo of a white swan which I know was done with my old camera in RGB and when it came up for keywording/categorizing the highlights were all blown, which I thought was weird, because it doesn't have blown highlights, so I deleted it from the queue and then asked about it. I'll look to see if I've still got their anser
The colour space can make a big difference to the viewer. I specifically asked that question at Crestock because many of the images displayed on "todays best" have a lot of blown highlights.
The simplest solution is to duplicate your file before you begin or before you assign/change the colour space. Some weird things can happen to the colour if convert back and forth
Most of my old files are in RGB, my more recent (stock) in sRGB because I'm finding more places are starting to use this. My print files remain in RGB because that's what the printer wants.
I've only run across one print company that doesn't want rgb - they want CMYK.